Know more

Our use of cookies

Cookies are a set of data stored on a user’s device when the user browses a web site. The data is in a file containing an ID number, the name of the server which deposited it and, in some cases, an expiry date. We use cookies to record information about your visit, language of preference, and other parameters on the site in order to optimise your next visit and make the site even more useful to you.

To improve your experience, we use cookies to store certain browsing information and provide secure navigation, and to collect statistics with a view to improve the site’s features. For a complete list of the cookies we use, download “Ghostery”, a free plug-in for browsers which can detect, and, in some cases, block cookies.

Ghostery is available here for free:

You can also visit the CNIL web site for instructions on how to configure your browser to manage cookie storage on your device.

In the case of third-party advertising cookies, you can also visit the following site:, offered by digital advertising professionals within the European Digital Advertising Alliance (EDAA). From the site, you can deny or accept the cookies used by advertising professionals who are members.

It is also possible to block certain third-party cookies directly via publishers:

Cookie type

Means of blocking

Analytical and performance cookies

Google Analytics

Targeted advertising cookies


The following types of cookies may be used on our websites:

Mandatory cookies

Functional cookies

Social media and advertising cookies

These cookies are needed to ensure the proper functioning of the site and cannot be disabled. They help ensure a secure connection and the basic availability of our website.

These cookies allow us to analyse site use in order to measure and optimise performance. They allow us to store your sign-in information and display the different components of our website in a more coherent way.

These cookies are used by advertising agencies such as Google and by social media sites such as LinkedIn and Facebook. Among other things, they allow pages to be shared on social media, the posting of comments, and the publication (on our site or elsewhere) of ads that reflect your centres of interest.

Our EZPublish content management system (CMS) uses CAS and PHP session cookies and the New Relic cookie for monitoring purposes (IP, response times).

These cookies are deleted at the end of the browsing session (when you log off or close your browser window)

Our EZPublish content management system (CMS) uses the XiTi cookie to measure traffic. Our service provider is AT Internet. This company stores data (IPs, date and time of access, length of the visit and pages viewed) for six months.

Our EZPublish content management system (CMS) does not use this type of cookie.

For more information about the cookies we use, contact INRA’s Data Protection Officer by email at or by post at:

24, chemin de Borde Rouge –Auzeville – CS52627
31326 Castanet Tolosan CEDEX - France

Dernière mise à jour : Mai 2018

Menu Logo Principal

Home page


Dynamics of Bacteriophages Genomes




The Phage team was launched in 2010 and has around 10 members, among which 6 have permanent positions (2 technicians, 1 research engineer, 2 senior researchers and 1 research director). We study phage genome dynamics by a combination of molecular, ecological and bio-informatics approaches.

Three senior researchers lead complementary and interconnected projects within the team:


François Lecointe leads projects aiming at deciphering phage recombination mechanisms able to repair DNA  double strand breaks, a source of toxicity but also of evolution.

He focuses his research on end joining pathways and characterizes cross-talks between bacterial and phage recombination  pathways.


Marianne De Paepe leads projects related to the impact of temperate phages on bacterial ecology, mainly by characterizing phage and bacterial population dynamics in simplified environments mimicking the gut microbiota, with Escherichia coli, Faecalibacterium prausnitzii, and Roseburia intestinalis.

She is interested in deciphering the evolutionary pressures and mechanisms that drive temperate phage evolution in the gut environment.


Marie-Agnès Petit leads phage culturomics projects starting from viromes on genera such as Escherichia, Roseburia, Bifidobacterium, Enterococcus.

She also develops tools to annotate phage genomes and perform comparative genomics analyzes. She is interested in improving existing bio-informatics tools to make them fit for phages. 




TEAM viewer (2017)




Phage team, bat 442, INRA, domaine de Vilvert, 78350 Jouy en Josas


01 34 65 20 77 (MAP) or 01 34 65 20 81 (FL and MDP)


marie-agnes.petit, francois.lecointe, or marianne.depaepe followed by


  • ANR Persist3R (2019-2021)
  • JPI Earlyvir (2015-2018)
  • Fondation pour la Recherche Médicale, J. Cornuault PhD's 4th year  (2017-2018)
  • ANR ASTRID ResisPhage (2014-2016)
  • Fondation François Aupetit (2015-2016)
  • ANR BLANC Dynamophage (2011-2014)
  • Fondation pour la Recherche Médicale (2010-2012)

See also

  • Visit the web site Phagonaute, to browse phage genomes and visualize distant homologies within a genomic window
  • Also, have a look at the VIRFAM web site of our collaborator Raphaël Guerois to classify phages by their connector module, and to predict phage-encoded recombinases.