Know more

Our use of cookies

Cookies are a set of data stored on a user’s device when the user browses a web site. The data is in a file containing an ID number, the name of the server which deposited it and, in some cases, an expiry date. We use cookies to record information about your visit, language of preference, and other parameters on the site in order to optimise your next visit and make the site even more useful to you.

To improve your experience, we use cookies to store certain browsing information and provide secure navigation, and to collect statistics with a view to improve the site’s features. For a complete list of the cookies we use, download “Ghostery”, a free plug-in for browsers which can detect, and, in some cases, block cookies.

Ghostery is available here for free:

You can also visit the CNIL web site for instructions on how to configure your browser to manage cookie storage on your device.

In the case of third-party advertising cookies, you can also visit the following site:, offered by digital advertising professionals within the European Digital Advertising Alliance (EDAA). From the site, you can deny or accept the cookies used by advertising professionals who are members.

It is also possible to block certain third-party cookies directly via publishers:

Cookie type

Means of blocking

Analytical and performance cookies

Google Analytics

Targeted advertising cookies


The following types of cookies may be used on our websites:

Mandatory cookies

Functional cookies

Social media and advertising cookies

These cookies are needed to ensure the proper functioning of the site and cannot be disabled. They help ensure a secure connection and the basic availability of our website.

These cookies allow us to analyse site use in order to measure and optimise performance. They allow us to store your sign-in information and display the different components of our website in a more coherent way.

These cookies are used by advertising agencies such as Google and by social media sites such as LinkedIn and Facebook. Among other things, they allow pages to be shared on social media, the posting of comments, and the publication (on our site or elsewhere) of ads that reflect your centres of interest.

Our EZPublish content management system (CMS) uses CAS and PHP session cookies and the New Relic cookie for monitoring purposes (IP, response times).

These cookies are deleted at the end of the browsing session (when you log off or close your browser window)

Our EZPublish content management system (CMS) uses the XiTi cookie to measure traffic. Our service provider is AT Internet. This company stores data (IPs, date and time of access, length of the visit and pages viewed) for six months.

Our EZPublish content management system (CMS) does not use this type of cookie.

For more information about the cookies we use, contact INRA’s Data Protection Officer by email at or by post at:

24, chemin de Borde Rouge –Auzeville – CS52627
31326 Castanet Tolosan CEDEX - France

Dernière mise à jour : Mai 2018

Menu Logo Principal

Home page


Marianne De Paepe

Marianne De Paepe
Researcher (CR)

Research interests

Temperate phages are ubiquitous parasites of bacteria, that greatly impact bacterial populations. In order to understand their impact on bacterial ecology, I study mainly two aspects of temperate phages: their mutation rate and the mortality they induce on gut bacteria. This last aspect is studied using gnotoxenic mice, these very simplified gut environments unabling to obtain quantitative aspects of bacterial lysis.

Main publications

Cornuault, J.K., Petit M.A., Mariadassou M., Benevides L., Moncaut E., Langella P., Sokol H., De Paepe M. (2018) Phages infecting Faecalibacterium prausnitzii belong to novel viral genera that help to decipher intestinal viromes. Microbiome Apr 3;6(1):65

Diard, M., Bakkeren, E., Cornuault JK., Moor K., Hausmann A., Sellin ME., Loverdo C., Aertsen A., Ackermann M., De Paepe M., Slack E., Hardt WD. Inflammation boosts bacteriophage transfer between Salmonella spp. Science. 2017 Mar 17;355(6330):1211-1215. DOU: 10.1126/science.aaf8451.

De Paepe, M., Moncaut, E., Son, O., S., Langella, P., Petit, M. A. (2016): Carriage of λ Latent Virus Is Costly for Its Bacterial Host due to Frequent Reactivation in Monoxenic Mouse Intestine. PLoS Genet 12(2): e1005861

De Paepe, M., Hutinet G., Son, O., Amarir, J. and Petit, M.A. (2014) Temperate phages acquire DNA from defective prophages by relaxed homologous recombination. PloS Genetics 10(3):e1004181

De Paepe M., Hutinet G., Son O., Amarir-Bouhram J., Schbath S., Petit M. A. (2014) Temperate phages acquire DNA from defective prophages by relaxed homologous recombination: the role of Rad52-like recombinases. PloS Genetics 10(3):e1004181

De Paepe M, Leclerc M, Tinsley CR, Petit MA. (2014) Bacteriophages: an underestimated role in human and animal health? Front Cell Infect Microbiol. 28(4):39
De Paepe, M., Gaboriau-Routhiau, V., Rainteau, D., Taddei, F. and Cerf-Bensussan, N. (2011) Trade-off between bile resistance and nutritional competence drives diversification in the mouse gut. PLoS Genetics,7, e6.
De Paepe M*, De Monte S*, Robert L, Lindner AB, Taddei F (2010) Emergence of variability in isogenic Escherichia coli populations infected by a filamentous virus. PLoS One 5(7): e11823
Giraud A, Arous S*, De Paepe M*, Gaboriau-Routhiau V, Bambou JC, Rakotobe S, Lindner AB, Taddei F, Cerf-Bensussan N (2008) Dissecting the genetic components of adaptation of Escherichia coli to the mouse gut. PLoS Genetics 4(1): e2
* These authors participated equally to the work
De Paepe M, Taddei F (2006) Viruses' Life History: Towards a Mechanistic Basis of a Trade-Off between Survival and Reproduction among Phages. PLoS Biology 4(7): e193
Brown SP, Le Chat L, De Paepe M, Taddei F (2006) Ecology of microbial invasions: amplification allows virus carriers to invade more rapidly when rare. Current Biology 16(20): 2048-2052