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INRA
24, chemin de Borde Rouge –Auzeville – CS52627
31326 Castanet Tolosan CEDEX - France

Dernière mise à jour : Mai 2018

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Publications

Bierne H, Milohanic E, Kortebi M.
To be cytosolic or vacuolar: the double life of Listeria monocytogenes 
Front. Cell. Infect. Microbiol. 2018. 8:136. doi: 10.3389/fcimb.2018.00136

Kortebi M, Milohanic E, Mitchell G, Péchoux C, Prevost MC, Cossart P, Bierne H.
Listeria monocytogenes switches from dissemination to persistence by adopting a vacuolar lifestyle in epithelial cells.
PLoS Pathog. 2017 Nov 30;13(11):e1006734. doi: 10.1371/journal.ppat.1006734.

Bierne H. Cross Talk between bacteria and the host epigenetic machinery.
Chapter from "Epigenetics of Infectious Diseases"(pp.113-158).  May 2017. Springer International Publishing, Editors: Walter Doerfler, Josep Casadesús.
DOI 10.1007/978-3-319-55021-3_6

Bierne H, Nielsen-LeRoux C.
Is there a transgenerational inheritance of host resistance against pathogens? Lessons from the Galleria mellonella-Bacillus thuringiensis interaction model.
Virulence. 2017 Jul 31:1-4. doi: 10.1080/21505594.2017.1356538. 

Dramsi S, Bierne H.
Spatial Organization of Cell Wall-Anchored Proteins at the Surface of Gram-Positive Bacteria.
Curr Top Microbiol Immunol. 2017;404:177-201. doi: 10.1007/82_2016_4.

Lakisic G, Lebreton A, Pourpre R, Wendling O, Libertini E, Radford EJ, Le Guillou M, Champy MF, Wattenhofer-Donzé M, Soubigou G, Ait-Si-Ali S, Feunteun J, Sorg T, Coppée JY, Ferguson-Smith AC, Cossart P, Bierne H.
Role of the BAHD1 Chromatin-Repressive Complex in Placental Development and Regulation of Steroid Metabolism.
PLoS Genetics. 2016 Mar 3;12(3):e1005898.

Libertini E, Lebreton A, Lakisic G, Dillies MA, Beck S, Coppée JY, Cossart P,  Bierne H.
Overexpression of the Heterochromatinization Factor BAHD1 in HEK293 Cells Differentially Reshapes the DNA Methylome on Autosomes and X Chromosome.
Frontiers Genetics. 2015 Dec 6; http://dx.doi.org/10.3389/fgene.2015.00339

Kentache T, Milohanic E, Cao TN, Mokhtari A, Aké FM, Ma Pham QM, Joyet P, Deutscher J.
Transport and Catabolism of Pentitols by Listeria monocytogenes.
J Mol Microbiol Biotechnol. 2016;26(6):369-380.

Zébré AC, Aké FM, Ventroux M, Koffi-Nevry R, Noirot-Gros MF, Deutscher J, Milohanic E.
Interaction with enzyme IIBMpo (EIIBMpo) and phosphorylation by phosphorylated EIIBMpo exert antagonistic effects on the transcriptional activator ManR of Listeria monocytogenes.
J. Bacteriol. 2015 May;197(9):1559-72. 

Radoshevich L, Impens F, Ribet D, Quereda JJ, Nam Tham T, Nahori MA, Bierne H, Dussurget O, Pizarro-Cerdá J, Knobeloch KP, Cossart P
ISG15 counteracts Listeria monocytogenes infection.
Elife. 2015 Aug 11;4. doi: 10.7554/eLife.06848.

Odendall C, Dixit E, Stavru F, Bierne H, Franz KM, Durbin AF, Boulant S, Gehrke L, Cossart P, Kagan JC.
Diverse intracellular pathogens activate type III interferon expression from peroxisomes.
Nature Immunol. 2014 Jun 22. doi: 10.1038/ni.2915.

Personnic N, Lakisic G, Gouin E, Rousseau A, Gautreau A, Cossart P, Bierne H.
A role for Ral GTPase-Activating-Protein subunit β in mitotic regulation.
FEBS J. 2014 May 11. doi: 10.1111/febs.12836.

Dussurget O, Bierne H, Cossart P.
The bacterial pathogen Listeria monocytogenes and the interferon family: type I, type II and type III interferons.
Front Cell Infect Microbiol. 2014 Apr 28;4:50.

Bécavin C, Bouchier C, Lechat P, Archambaud C, Creno S, Gouin E, Wu Z, Kühbacher A, Brisse S, Pucciarelli MG, García-del Portillo F, Hain T, Portnoy DA, Chakraborty T, Lecuit M, Pizarro-Cerdá J, Moszer I, Bierne H, Cossart P.
Comparison of widely used Listeria monocytogenes strains EGD, 10403S, and EGD-e highlights genomic variations underlying differences in pathogenicity.
MBio. 2014 Mar 25;5(2):e00969-14.

Bierne H, Cossart P.
Des microbes à l'attaque du noyau.
Pour la Science. Mars 2014. N°437. p46-53.

Lebreton A, Job V, Ragon M, Le Monnier A, Dessen A, Cossart P, Bierne H.
Structural basis for the inhibition of the chromatin repressor BAHD1 by the bacterial nucleomodulin LntA.
MBio. 2014 Jan 21;5(1):e00775-13.

Bierne H.
Nuclear microbiology--bacterial assault on the nucleolus.
EMBO Rep. 2013 Aug;14(8):663-4.

Tsai YH, Disson O, Bierne H, Lecuit M.
Murinization of internalin extends its receptor repertoire, altering Listeria monocytogenes cell tropism and host responses.
PLoS Pathog. 2013;9(5):e1003381. 

Bierne H, Hamon M, Cossart P.
Epigenetics and bacterial infections.
Cold Spring Harb Perspect Med. 2012 Dec 1;2(12):a010272.

Bierne H, Dramsi S.
Spatial positioning of cell wall-anchored virulence factors in Gram-positive bacteria.
Curr Opin Microbiol. 2012 Dec;15(6):715-23.

Radoshevich L, Bierne H, Ribet D, Cossart P.
The New Microbiology: a conference at the Institut de France.
C R Biol. 2012 Aug;335(8):514-9.

Bierne H, Travier L, Mahlakõiv T, Tailleux L, Subtil A, Lebreton A, Paliwal A, Gicquel B, Staeheli P, Lecuit M, Cossart P.
Activation of type III interferon genes by pathogenic bacteria in infected epithelial cells and mouse placenta.
PLoS One. 2012;7(6):e39080.

Bierne H, Cossart P. When bacteria target the nucleus: the emerging family of nucleomodulins.
Cell Microbiol. 2012 May;14(5):622-33.

Lebreton A,  Bierne H, Cossart P.
Les multiples stratégies de Listeria.
Pour la Science, Février 2012. N°412. p42-49

Lebreton A, Cossart P, Bierne H.
Bacteria tune interferon responses by playing with chromatin.
Virulence. 2012 Jan-Feb;3(1):87-91.

Bruck S, Personnic N, Prevost MC, Cossart P, Bierne H.
Regulated shift from helical to polar localization of Listeria monocytogenes cell wall-anchored proteins.
J Bacteriol. 2011 Sep;193(17):4425-37.

Lebreton A, Lakisic G, Job V, Fritsch L, Tham TN, Camejo A, Matteï PJ, Regnault B, Nahori MA, Cabanes D, Gautreau A, Ait-Si-Ali S, Dessen A, Cossart P, Bierne H.
A bacterial protein targets the BAHD1 chromatin complex to stimulate type III interferon response.
Science. 2011 Mar 11;331(6022):1319-21.