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INRAE

24, chemin de Borde Rouge -Auzeville - CS52627 31326 Castanet Tolosan cedex - France

Last update: May 2021

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Publications

PUBLICATIONS 2022

C. Roussel, B. Ebel, E. Munier, D. Michelon, F. Martin-Dejardin, E. Beuvier, J. De Coninck, P. Gaudu, R. Cachon (2022) Green strategies to control redox potential in the fermented food industry. Food Res Int. in press.

C. Lambert, C. Poyart, A. Gruss, A. Fouet (2022) FabT, a Bacterial Transcriptional Repressor That Limits Futile Fatty Acid Biosynthesis. Microbiol Mol Biol Rev., in press. 

F. Rizzotto, Z.Z. Vasiljevic, G. Stanojevic, M.P. Dojcinovic, I. Jankovic-Castvan, J.D. Vujancevic, N.B. Tadic, G.O. Brankovic, A. Magniez, J. Vidic*, M.V. Nikolic (2022) Antioxidant and Cell-friendly Fe2TiO5 Nanoparticles for Food Packaging Application. Food Chem., in press

T. Franza, P. Gaudu (2022) Quinones: More Than Electron Shuttles. Res. Microbiol. 103953.       

A. Cossettini, J. Vidic , M. Maifreni, M. Marino, D. Pinamonti, M. Manzano  (2022) Rapid detection of Listeria monocytogenes, Salmonella, Campylobacter spp., and Escherichia coli in food using biosensors. Food Control, 137, 108962.

Z. Kotsiri, J. Vidic, A. Vantarakis (2022) Applications of biosensors for bacteria and viruses detection in food and water – A systematic review. J. Environ. Sci., 111, 367-379. 

PUBLICATIONS 2021

B. Cesselin, C. Henry, A. Gruss, K. Gloux, P. Gaudu P. (2021) Mechanisms of acetoin toxicity and adaptive responses in an acetoin-producing species, Lactococcus lactis. Appl Environ Microbiol. 2021, in press.

I. Bobrinetskiy, M. Radovic, F. Rizzotto, P. Vizzini, S. Jaric, Z. Pavlovic, V. Radonic, M. V. Nikolic, J. Vidic (2021) Advances in Nanomaterials-Based Electrochemical Biosensors for Foodborne Pathogen Detection. 11, 2700.  

P. Vizzini, J. Vidic, M. Manzano (2021) Enrichment Free qPCR for Rapid Identification and Quantification of Campylobacter jejuni, C. coli, C. lari and C. upsaliensis in Chicken Meat Samples by a New Couple of Primers. Foods, 10(10), 2341.

Vidic J, Manazano M (2021) Electrochemical biosensors for rapid pathogen detection. Curr Opinion Electrochem, 100750.

Franza T, Rogstam A, Thiyagarajan S, Sullivan MJ, Derré-Bobillot A, Bauer MC, Goh KGK, Da Cunha V, Glaser P, Logan DT, Ulett GC, von Wachenfeldt C, Gaudu P. (2021) NAD+ pool depletion as a signal for the Rex regulon involved in Streptococcus agalactiae virulence. PLoS Pathog. 2021, 17(8): e1009791. 

M.V. Nikolic, Z.Z. Vasiljevic, S. Auger, J. Vidic (2021) Metal Oxide Nanoparticles for Safe Active and Intelligent Food Packaging. Trends Food Sci. Tech. 116, 655-668.   

Marin M, Nikolic MV, Vidic J (2021) Rapid Point-of-Need Detection of Bacteria and their Toxins in Food using Gold Nanoparticles. Com. Rev. Food. Sci. F., in press.

Hays C, Lambert C, Brinster S, Lamberet G, du Merle L, Gloux K, Gruss A, Poyart C, Fouet A. (2021) Type II fatty acid synthesis pathway and cyclopropane ring formation are dispensable during Enterococcus faecalis systemic infection. J Bacteriol. 2021 JB0022121.          

Saillant V, Lipuma D, Ostyn E, Joubert L, Boussac A, Guerin H, Brandelet G, Arnoux P, Lechardeur D. (2021) A Novel Enterococcus faecalis Heme Transport Regulator (FhtR) Senses Host Heme To Control Its Intracellular Homeostasis. mBio; 2021, 12, e03392-20      

Balbinot S, Srivastav AM, Vidic J, Abdulhalim I, Manzano M (2021) Plasmonic biosensors for food control. Trends Food Sci. Tech. 111, 128-140.

Pathania A, Anba-Mondoloni J, Gominet M, Halpern D, Dairou J, Dupont L, Lamberet G, Trieu-Cuot P, Gloux K, Gruss A. (2021) (p)ppGpp/GTP and Malonyl-CoA Modulate Staphylococcus aureus Adaptation to FASII Antibiotics and Provide a Basis for Synergistic Bi-Therapy. mBio. 2021, 12, e03193-20.

N. Omerović, M. Djisalov, K. Živojević, M. Mladenović, J. Vunduk, I. Milenković, N. Ž. Knežević, I. Gadjanski, J. Vidić (2021) Antimicrobial nanoparticles and biodegradable polymer composites for active food packaging applications. Compr. Rev. Food Sci Food Saf. 20, 2428-2454.

Halpern D, Morvan C, Derré-Bobillot A, Meylheuc T, Guillemet M, Rabot S, Gruss A. (2021) Do Primocolonizing Bacteria Enable Bacteroides thetaiotaomicron Intestinal Colonization Independently of the Capacity To Consume Oxygen? mSphere, 2021, 6, e00232-19.

PUBLICATIONS 2020

Gruss A. (2020) A FAS solution to a DEAD case. PLoS Genet. 2020, 16, e1008842.

PUBLICATIONS 2019

Kénanian G, Morvan C, Weckel A, Pathania A, Anba-Mondoloni J, Halpern D, Gaillard M, Solgadi A, Dupont L, Henry C, Poyart C, Fouet A, Lamberet G, Gloux K, Gruss A. (2019) Permissive Fatty Acid Incorporation Promotes Staphylococcal Adaptation to FASII Antibiotics in Host Environments. Cell Rep. 2019, 29, 3974-3982.e4.

Gaudu P, Yamamoto Y, Jensen PR, Hammer K, Lechardeur D, Gruss A. (2019) Genetics of Lactococci. Microbiol Spectr. 2019, 7.

PUBLICATIONS 2018

Cesselin B, Garrigues C, Pedersen MB, Roussel C, Gruss A, Gaudu P. Task Distribution between Acetate and Acetoin Pathways to Prolong Growth in Lactococcus lactis under Respiration Conditions. Appl Environ Microbiol. 2018 Jul 20.

Lencina AM, Franza T, Sullivan MJ, Ulett GC, Ipe DS, Gaudu P, Gennis RB, Schurig-Briccio LA. (2018). Type 2 NADH Dehydrogenase Is the Only Point of Entry for Electrons into the Streptococcus agalactiae Respiratory Chain and Is a Potential Drug Target. MBio. 9(4). pii: e01034-18. doi: 10.1128/mBio.01034-18.

Boudjemaa R, Cabriel C, Dubois-Brissonnet F, Bourg N, Dupuis G, Gruss A, Leveque-Fort S, Briandet R, Fontaine-Aupart MP and Steenkeste K. (2018) Failure of daptomycin to kill Staphylococcus aureus: impact of bacterial membrane fatty acid composition. Antimicrob Agents Chemother. in press

Fojcik C, Arnoux P, Ouerdane L, Aigle M, Alphonsi L, Borezée-Durant E. (2018) Independent and cooperative regulation of staphylopine biosynthesis and trafficking by Fur and Zur. Mol Microbiol doi: 10.1111/mmi.13927.

PUBLICATIONS 2017

Morvan C, Halpern D, Kenanian G, Pathania A, Anba-Mondoloni J, Lamberet G, Gruss A, Gloux K. The Staphylococcus aureus FASII bypass escape route from FASII inhibitors. Biochimie. 2017 Oct;141:40-46

Gloux K, Guillemet M, Soler C, Morvan C, Halpern D, Pourcel C, Vu Thien H, Lamberet G, Gruss A. Clinical Relevance of Type II Fatty Acid Synthesis Bypass in Staphylococcus aureus. Antimicrob Agents Chemother. 2017 Apr 24;61(5)

Joubert L, Dagieu JB, Fernandez A, Derré-Bobillot A, Borezée-Durant E, Fleurot I, Gruss A, Lechardeur D. Visualization of the role of host heme on the virulence of the heme auxotroph Streptococcus agalactiae. Sci Rep. 2017 Jan 16

Lhospice S, Gomez NO, Ouerdane L, Brutesco C, Ghssein G, Hajjar C, Liratni A, Wang S, Richaud P, Bleves S, Ball G, Borezée-Durant E, Lobinski R, Pignol D, Arnoux P, Voulhoux R. (2017) Pseudomonas aeruginosa zinc uptake in chelating environment is primarily mediated by the metallophore pseudopaline. Sci Rep.7(1):17132. doi: 10.1038/s41598-017-16765-9.

PUBLICATIONS 2016

Moulin P, Patron K, Cano C, Zorgani MA, Camiade E, Borezée-Durant E, Rosenau A, Mereghetti L, Hiron A.(2016) The Adc/Lmb System Mediates Zinc Acquisition in Streptococcus agalactiae and Contributes to Bacterial Growth and Survival. J Bacteriol. 198(24):3265-3277.

Morvan C, Halpern D, Kénanian G, Hays C, Anba-Mondoloni J, Brinster S, Kennedy S, Trieu-Cuot P, Poyart C, Lamberet G, Gloux K, Gruss A. Environmental fatty acids enable emergence of infectious Staphylococcus aureus resistant to FASII-targeted antimicrobials. Nat Commun. 2016 Oct 5

Franza, T., Delavenne, E., Derré-Bobillot, A., Juillard, V., Boulay, M., Demey, E., Vinh, J., Lamberet, G., Gaudu, P. (2016). A partial metabolic pathway enables group b streptococcus to overcome quinone deficiency in a host bacterial community. Molecular Microbiology, 102 (1), 81-91

Ghssein G, Brutesco C, Ouerdane L, Fojcik C, Izaute A, Wang S, Hajjar C, Lobinski R, Lemaire D, Richaud P, Voulhoux R, Espaillat A, Cava F, Pignol D, Borezée-Durant E, Arnoux P (2016). Biosynthesis of a broad-spectrum nicotianamine-like metallophore in Staphylococcus aureus. Science 352:1105-9.

Gloux K, Anba-Mondoloni J. 2016. Unique beta-Glucuronidase locus in gut microbiomes of Crohn's disease patients and unaffected first-degree relatives. PLoS One 11

PUBLICATIONS 2015

Pérez-Pascual D, Gaudu P, Fleuchot B, Besset C, Rosinski-Chupin I, Guillot A, Monnet V, Gardan R. (2015) RovS and its associated signaling peptide form a cell-to-cell communication system required for Streptococcus agalactiae pathogenesis. MBio. 6(1). pii: e02306-14.

Lebrette H, Borezée-Durant E, Martin L, Richaud P, Boeri Erba E, Cavazza C. Novel insights into nickel import in Staphylococcus aureus: the positive role of free histidine and structural characterization of a new thiazolidine-type nickel chelator. Metallomics. 2015 Jan 22

Roussel C, Cesselin B, Cachon R, Gaudu P.Characterization of two Lactococcus lactis zinc membrane proteins, Llmg_0524 and Llmg_0526, and role of Llmg_0524 in cell wall integrity.BMC Microbiol. 2015 Oct 30;15:246.

Halpern D,  Gruss A (2015). A sensitive bacterial-growth-based test reveals how intestinal Bacteroides meet their porphyrin requirement. BMC microbiology, 15(1), 1.

PUBLICATIONS 2014

Joubert L, Derré-Bobillot A, Gaudu P, Gruss A, Lechardeur D. (2014) HrtBA and menaquinones control haem homeostasis in Lactococcus lactis. Mol Microbiol. 93(4):823-33

Moon AF, Gaudu P, Pedersen LC. (2014) Structural characterization of the virulence factor nuclease A from Streptococcus agalactiae. Acta Crystallogr D Biol Crystallogr. 70(Pt 11):2937-49.

Fleurot I, Aigle M, Fleurot R, Darrigo C, Hennekinne JA, Gruss A, Borezée-Durant E, Delacroix-Buchet A. Following pathogen development and gene expression in a food ecosystem: the case of a Staphylococcus aureus isolate in cheese. Appl Environ Microbiol. 2014 Aug;80(16):5106-15

Lebrette H, Brochier-Armanet C, Zambelli B, de Reuse H, Borezée-Durant E, Ciurli S, Cavazza C. Promiscuous nickel import in human pathogens: structure, thermodynamics, and evolution of extracytoplasmic nickel-binding proteins. Structure. 2014 Oct 7;22(10):1421-32

PUBLICATIONS 2013

Guinebretiere MH, Auger S, Galleron N, Contzen M, De Sarrau B, De Buyser ML, Lamberet G, Fagerlund A, Granum PE, Lereclus D, De Vos P, Nguyen-The C, Sorokin A (2013) Bacillus cytotoxicus sp. nov. is a novel thermotolerant species of the Bacillus cereus Group occasionally associated with food poisoning. Int J Syst Evol Microbiol 63(Pt 1): 31-40

Remy L, Carriere M, Derre-Bobillot A, Martini C, Sanguinetti M, Borezee-Durant E (2013) The Staphylococcus aureus Opp1 ABC transporter imports nickel and cobalt in zinc-depleted conditions and contributes to virulence. Mol Microbiol 87(4): 730-743

Derre-Bobillot A, Cortes-Perez NG, Yamamoto Y, Kharrat P, Couve E, Da Cunha V, Decker P, Boissier MC, Escartin F, Cesselin B, Langella P, Bermudez-Humaran LG, Gaudu P (2013) Nuclease A (Gbs0661), an extracellular nuclease of Streptococcus agalactiae, attacks the neutrophil extracellular traps and is needed for full virulence. Mol Microbiol 89(3): 518-531

PUBLICATIONS 2012

Lechardeur D, Cesselin B, Liebl U, Vos MH, Fernandez A, Brun C, Gruss A, Gaudu P (2012) Discovery of intracellular heme-binding protein HrtR, which controls heme efflux by the conserved HrtB-HrtA transporter in Lactococcus lactis. J Biol Chem 287(7): 4752-4758

Rochat T, Boudebbouze S, Gratadoux JJ, Blugeon S, Gaudu P, Langella P, Maguin E (2012) Proteomic analysis of spontaneous mutants of Lactococcus lactis: Involvement of GAPDH and arginine deiminase pathway in H2O2 resistance. Proteomics 12(11): 1792-1805

Gruss A, Borezee-Durant E, Lechardeur D (2012) Environmental heme utilization by heme-auxotrophic bacteria. Adv Microb Physiol 61: 69-124

Pedersen MB, Gaudu P, Lechardeur D, Petit MA, Gruss A (2012) Aerobic respiration metabolism in lactic acid bacteria and uses in biotechnology. Annu Rev Food Sci Technol 3: 37-58

Houry A, Gohar M, Deschamps J, Tischenko E, Aymerich S, Gruss A, Briandet R (2012) Bacterial swimmers that infiltrate and take over the biofilm matrix. Proc Natl Acad Sci U S A 109(32): 13088-13093

PUBLICATIONS 2011

Lechardeur D, Cesselin B, Fernandez A, Lamberet G, Garrigues C, Pedersen M, Gaudu P, Gruss A (2011) Using heme as an energy boost for lactic acid bacteria. Curr Opin Biotechnol 22(2): 143-149

Fouquier d’Hérouel A, Wessner F, Halpern D, Ly-Vu J. Kennedy S. Serror P, Aurell E, and Repoila F (2011). A simple and efficient method to search for selected primary transcripts: noncoding- and antisense RNAs in the human pathogen Enterococcus faecalis. Nucl. Ac. Res. Doi: 10.1093/nar/gkr012

PUBLICATIONS 2010

Brinster S, Lamberet G, Staels B, Trieu-Cuot P, Gruss A, Poyart C (2010) Essentiality of FASII pathway for Staphylococcus aureus. Reply. Nature 463: E4-E5

Hiron A, Posteraro B, Carriere M, Remy L, Delporte C, La Sorda M, Sanguinetti M, Juillard V, Borezee-Durant E (2010) A nickel ABC-transporter of Staphylococcus aureus is involved in urinary tract infection. Mol Microbiol 77(5): 1246-1260

Fernandez A, Lechardeur D, Derre-Bobillot A, Couve E, Gaudu P, Gruss A (2010) Two coregulated efflux transporters modulate intracellular heme and protoporphyrin IX availability in Streptococcus agalactiae. PLoS Pathog 6(4): e1000860

Duquenne M, Fleurot I, Aigle M, Darrigo C, Borezee-Durant E, Derzelle S, Bouix M, Deperrois-Lafarge V, Delacroix-Buchet A (2010) Tool for quantification of staphylococcal enterotoxin gene expression in cheese. Appl Environ Microbiol 76(5): 1367-1374

Bohn C, Rigoulay C, Chabelskaya S, Sharma CM, Marchais A, Skorski P, Borezee-Durant E, Barbet R, Jacquet E, Jacq A, Gautheret D, Felden B, Vogel J, Bouloc P (2010) Experimental discovery of small RNAs in Staphylococcus aureus reveals a riboregulator of central metabolism. Nucleic Acids Res 38(19): 6620-6636

Lechardeur D, Fernandez A, Robert B, Gaudu P, Trieu-Cuot P, Lamberet G, Gruss A (2010) The 2-Cys peroxiredoxin alkyl hydroperoxide reductase c binds heme and participates in its intracellular availability in Streptococcus agalactiae. J Biol Chem 285(21): 16032-16041

PUBLICATIONS 2009

Lopez de Felipe F, Gaudu P (2009) Multiple control of the acetate pathway in Lactococcus lactis under aeration by catabolite repression and metabolites. Appl Microbiol Biotechnol 82(6): 1115-1122

Cesselin B, Ali D, Gratadoux JJ, Gaudu P, Duwat P, Gruss A, El Karoui M (2009) Inactivation of the Lactococcus lactis high-affinity phosphate transporter confers oxygen and thiol resistance and alters metal homeostasis. Microbiology 155(Pt 7): 2274-2281

Borezee-Durant E, Hiron A, Piard JC, Juillard V (2009) Dual role of the oligopeptide permease Opp3 during growth of Staphylococcus aureus in milk. Appl Environ Microbiol 75(10): 3355-3357 *work was realized before joining our lab

Brinster S, Lamberet G, Staels B, Trieu-Cuot P, Gruss A, Poyart C (2009) Type II fatty acid synthesis is not a suitable antibiotic target for Gram-positive pathogens. Nature 458(7234): 83-86

PUBLICATIONS 2008

Pedersen MB, Garrigues C, Tuphile K, Brun C, Vido K, Bennedsen M, Mollgaard H, Gaudu P, Gruss A (2008) Impact of aeration and heme-activated respiration on Lactococcus lactis gene expression: identification of a heme-responsive operon. J Bacteriol 190(14): 4903-4911

Rezaiki L, Lamberet G, Derre A, Gruss A, Gaudu P (2008) Lactococcus lactis produces short-chain quinones that cross-feed Group B Streptococcus to activate respiration growth. Mol Microbiol 67(5): 947-957

PUBLICATIONS 2007

Veiga, P, et al., SpxB regulates O-acetylation-dependent resistance of Lactococcus lactis peptidoglycan to hydrolysis. J Biol Chem, 2007. 282(27): p. 19342-54.

Hiron A, et al., Only one of four oligopeptide transport systems mediates nitrogen nutrition in Staphylococcus aureus. J Bacteriol, 2007. 189(14): p. 5119-29.

Halpern D, et al., Identification of DNA motifs implicated in maintenance of bacterial core genomes by predictive modeling. PLoS Genet, 2007. 3(9): p. 1614-21.

Bermudez-Humaran L.G, et al., Effects of intranasal administration of a leptin-secreting Lactococcus lactis recombinant on food intake, body weight, and immune response of mice. Appl Environ Microbiol, 2007. 73(16): p. 5300-7.

PUBLICATIONS 2006

Yamamoto Y, et al., Roles of environmental heme, and menaquinone, in streptococcus agalactiae. Biometals, 2006. 19(2): p. 205-10.

Yamamoto Y, et al., The Group B Streptococcus NADH oxidase Nox-2 is involved in fatty acid biosynthesis during aerobic growth and contributes to virulence. Mol Microbiol, 2006. 62(3): p. 772-85.

Rochat T, et al., Production of a heterologous nonheme catalase by Lactobacillus casei: an efficient tool for removal of H2O2 and protection of Lactobacillus bulgaricus from oxidative stress in milk. Appl Environ Microbiol, 2006. 72(8): p. 5143-9.

Nouaille S, et al., Complementation of the Lactococcus lactis secretion machinery with Bacillus subtilis SecDF improves secretion of staphylococcal nuclease. Appl Environ Microbiol, 2006. 72(3): p. 2272-9.

Garrigues C, et al., Getting high (OD) on heme. Nat Rev Microbiol, 2006. 4(4): p. c2; author reply c3.

PATENTS

Houry A, Gohar M, Deschamps J, Aymerich S; Gruss A, Briandet R. (2010) FR 10 60945 Procédé d'élimination d'un biofilm de microorganisme. Filing date 23/12/2010

Cesselin B, Lechardeur D, Gaudu P, Pedersen M, Garrigues C, Gruss A. (2011) EP11150342.1 Metalloprophyrin inducible promoter. Brevet INRA-Chr Hansen. In PCT. Filing date 06/01/2011

Gruss A, Halpern D (2014) EP1430738.1 A highly sensitive biologically based heme detection test. Filling date 15/12/2014

V. Radonic, J. Vidic, M. Radovic, I. Gadjanski: PLANAR ELECTRODE FOR BIOSENSORS REALIZED USING REPETITIVE FRACTAL GEOMETRY, P-2020/1065 NP.

P. Vizzini, M. Manzano, N. Ramarao, J. Vidic :  SONDA PER LA RIVELAZIONE DI INFEZIONI BATTERICHE, BI803E/RVP/rmc.

J. Vidic, C. Chaix, C. Farre, N. Ramarao, M. Manzano, P. Vizzini : PROCEDE ET SYSTEME POUR LA DETERMINATION DE LA PRESENCE ET/OU DE LA QUANTITE D’AU MOINS UN ANALYTE SUSCEPTIBLE D’ETRE CONTENU DANS UN ECHANTILLON; FR 20 05578