Know more

Our use of cookies

Cookies are a set of data stored on a user’s device when the user browses a web site. The data is in a file containing an ID number, the name of the server which deposited it and, in some cases, an expiry date. We use cookies to record information about your visit, language of preference, and other parameters on the site in order to optimise your next visit and make the site even more useful to you.

To improve your experience, we use cookies to store certain browsing information and provide secure navigation, and to collect statistics with a view to improve the site’s features. For a complete list of the cookies we use, download “Ghostery”, a free plug-in for browsers which can detect, and, in some cases, block cookies.

Ghostery is available here for free:

You can also visit the CNIL web site for instructions on how to configure your browser to manage cookie storage on your device.

In the case of third-party advertising cookies, you can also visit the following site:, offered by digital advertising professionals within the European Digital Advertising Alliance (EDAA). From the site, you can deny or accept the cookies used by advertising professionals who are members.

It is also possible to block certain third-party cookies directly via publishers:

Cookie type

Means of blocking

Analytical and performance cookies

Google Analytics

Targeted advertising cookies


The following types of cookies may be used on our websites:

Mandatory cookies

Functional cookies

Social media and advertising cookies

These cookies are needed to ensure the proper functioning of the site and cannot be disabled. They help ensure a secure connection and the basic availability of our website.

These cookies allow us to analyse site use in order to measure and optimise performance. They allow us to store your sign-in information and display the different components of our website in a more coherent way.

These cookies are used by advertising agencies such as Google and by social media sites such as LinkedIn and Facebook. Among other things, they allow pages to be shared on social media, the posting of comments, and the publication (on our site or elsewhere) of ads that reflect your centres of interest.

Our EZPublish content management system (CMS) uses CAS and PHP session cookies and the New Relic cookie for monitoring purposes (IP, response times).

These cookies are deleted at the end of the browsing session (when you log off or close your browser window)

Our EZPublish content management system (CMS) uses the XiTi cookie to measure traffic. Our service provider is AT Internet. This company stores data (IPs, date and time of access, length of the visit and pages viewed) for six months.

Our EZPublish content management system (CMS) does not use this type of cookie.

For more information about the cookies we use, contact INRA’s Data Protection Officer by email at or by post at:

24, chemin de Borde Rouge –Auzeville – CS52627
31326 Castanet Tolosan CEDEX - France

Dernière mise à jour : Mai 2018

Menu Logo Principal

Home page


Nalini Rama Rao

Nalini Rama Rao
Directrice de recherche, e-mail:

Dr. Nalini Rama Rao, curriculum vitae brevis

I am the head of the PIMs (Pathogen Interaction with Macrophages) team, constituted to date by 1 DR2, 1 CR1, 1 IR2, 1 TR, 2 Postdocs, 1 PhD Student and 2 master students. I am a cell biologist/microbiologist specialized in host-pathogen interactions. My double education as a Biotechnology Engineer (International biotechnology engineering) and as a researcher (PhD, Max Planck Institute, Germany) ensures the effective implementation of multidisciplinary projects. I gained knowledge on several bacterial systems during her Master/Engineer internship at Connaught Laboratory, Canada (vaccine design against Clamydia), my PhD at the MPI in Tübingen, Germany (patents on H. pylori virulence factors), my Post-doctorat at the Pasteur Institute (S. flexneri pathogenesis) and after my recruitment as a permanent scientist at INRA, Micalis (B. cereus interaction with host cells). My carrier allowed me to gain and appreciate international experiences. I undertook the supervision of 18 people in the last 10 years, including 5 phD thesis. My work led to 34 international publications, 3 patent applications, over 20 international congresses and various national and international collaborations. In 2014, I obtained from INRA a “grant of scientific excellence”.

I have been working on the interaction between B. cereus and host cells for the last 12 years and I am now a recognized expert on B. cereus virulence factors and host-pathogen interaction. I have recently published significant papers dealing with host-pathogen interaction, and specifically with the mechanism of bacterial defence against the host immune cells. I studied the role and the expression of several virulent determinants including hemolysins and proteases, in B. cereus motility, biofilm formation, adhesion to epithelial cells, cytotoxicity, macrophage escape and virulence using cellular and animal models. I developed models to search for markers that could differentiate pathogenic from non pathogenic B. cereus strains (IDEX 2016/2017 from FCS Paris Saclay). I am a WP leader of a European project targeting diagnosis of toxin producing bacteria (EJP-MedVet, 2017-2019)

I am also the leader of a more applied project towards antibiotic development (SATT-Paris Saclay project, 2016-2018). The goal of the project is to characterize new antimicrobials to fight against resistant bacteria, especially those leading to therapeutic impasses.

Finally, I took the opportunity of my moving in 2014 to the Micalis Institute in Jouy en Josas, to develop a new and ambitious project at the forefront of Human health. The goal of this innovative project is to decipher the role of the microbiota in the adaptation of an intestinal pathogen in its niche. This project is financially supported by the Inra Metaprogram MEM (MetaOmics of Microbial Ecosystems).


1996: Master in Cell and Molecular Biology (University of Strasbourg, France)

1996: Engineer Degree (ESBS, France, Germany, Switzerland)

2000: Ph.D. Max Planck Institute (University of Tübingen, Germany)

2010: HDR, Paris 7

2016: DR2, Inra Jouy en Josas

Current position: Since 2014, Team leader, MICALIS Unit (INRA), PIMS team


Previous employment:

1997-2000: PhD student, MPI Tübingen, Germany, T. Meyer/ S. Gray-Owen

2001-2003: Post-doctoral fellow, Institut Pasteur, Paris Unité U389, P. Sansonetti

2003-2014: CR1 INRA, Group leader, MICALIS Unit (INRA)

2014-present: DR2, team leader PIMs (Pathogen Interaction with Macrophages)


Team Management : Supervision of 5 phD students, 5 postdocs, 6 Masters, 6 under-graduates, 4 technicians, 1 Assistant Engineer, 1 research engineer and 1 senior scientist.

Teachning : Masters, Versailles-Saint Quentin university.

Communications :

-Over 20 oral and poster presentations at International Congresses.

-General public : Multi media comics,  Art and Science Project, Fondation Carasso 2016-2017.

 On going funds:

-EJP-Med Vet, Tox Detect (2017-2019, 2M, 200 k€ for PIMs)

-SATT Paris Saclay, NewMed, antimicrobial development (2016-2018, 650 k€).

-Idex Paris Saclay/Inra, IdexBc, diagnostics (2017-2018, 80k€)

-Metaprogramme MEM, MicrobNO (2017-2019, 50 k€)

-Metaprogramme MEM, MetafoldScan (2016-2018, 50 k€)

-Campus Prestige, Pierre and Marie Curie fellowship (2016-2018, post doc fellowship)

-IDI Paris Saclay (2016-2019, PhD fellowship)

-Hubert Curien Procope, Biologie Médecine Santé (2016-2017, 15 k€)

-Fondation Daniel et Nina Carasso. Art Citoyen, projet Arts et Sciences (2016-2017, 50 k€).

-IDEX FCS-Paris-Saclay (2015-2016, 80 k€).

 Publications: 36 publications in peer reviewed journals, 3 patents.3 cover illustrations.


5 major papers in last 5 years:

1- Lotte et al (2017) Emerging Infect Dis 23:845-48

2-Glasset, et al (2016) Eurosurveillance 21:48

3-Guillemet, et al. (2016) Scientific Reports, 6:29349

4-Darrigo et al (2016) PLoS One 11: e0163321

5-Ramarao et al (2014) Am J Infect Control, 42: 688-96


Awards: EMBO fellowship 2001-2003 


Nalini Rama Rao

Team leader: INRA-Micalis, PIMs team –

The MICALIS Institute (Microbiology for Food Safety and Health) aims at improving food quality and health control by providing an accurate knowledge on food contaminants.