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Back A, Rossignol T, Krier F, Nicaud J-M & Dhulster P (2016) High-throughput fermentation screening for the yeast Yarrowia lipolytica with real-time monitoring of biomass and lipid production. Microbial Cell Factories15: 147.

Dulermo R, Gamboa-Meléndez H, Ledesma‐Amaro R, Thevenieau F & Nicaud J-M (2016) Yarrowia lipolytica AAL genes are involved in peroxisomal fatty acid activation. Biochim Biophys Acta1861: 555-565.

Gajdoš P, Ledesma-Amaro R, Nicaud J-M, Čertík M & Rossignol T (2016) Overexpression of diacylglycerol acyltransferase in arrowia lipolytica affects lipid body size, number and distribution. FEMS Yeast Res16.

Ledesma-Amaro R & Nicaud J-M (2016) Metabolic Engineering for Expanding the Substrate Range of Yarrowia lipolytica. Trends Biotechnol34: 798-809.

Ledesma-Amaro R & Nicaud J-M (2016) Yarrowia lipolytica as a biotechnological chassis to produce usual and unusual fatty acids. Progress in Lipid Research61: 40-50.

Ledesma-Amaro R, Dulermo R, Niehus X & Nicaud J-M (2016) Combining metabolic engineering and process optimization to improve production and secretion of fatty acids. Metab Eng38: 38-46.

Ledesma-Amaro R, Lazar Z, Rakicka M, Guo Z, Fouchard F, Coq A-MC-L & Nicaud J-M (2016) Metabolic engineering of Yarrowia lipolytica to produce chemicals and fuels from xylose. Metab Eng38: 115-124.



Dulermo R, Gamboa-Melendez H, Ledesma-Amaro R, Thevenieau F & Nicaud JM (2015) Unraveling fatty acid transport and activation mechanisms in Yarrowia lipolytica. Biochim Biophys Acta 1851: 1202-1217.

Dulermo R, Dulermo T, Gamboa-Melendez H, Thevenieau F & Nicaud JM (2015) Role of Pex11p in Lipid Homeostasis in Yarrowia lipolytica. Eukaryot Cell 14: 511-525.

Dulermo R, Gamboa-Melendez H, Michely S, Thevenieau F, Neuveglise C & Nicaud JM (2015) The evolution of Jen3 proteins and their role in dicarboxylic acid transport in Yarrowia. Microbiologyopen 4: 100-120.

Dulermo T, Lazar Z, Dulermo R, Rakicka M, Haddouche R & Nicaud JM (2015) Analysis of ATP-citrate lyase and malic enzyme mutants of Yarrowia lipolytica points out the importance of mannitol metabolism in fatty acid synthesis. Biochim Biophys Acta 1851: 1107-1117.

Gajdos P, Nicaud JM, Rossignol T & Certik M (2015) Single cell oil production on molasses by Yarrowia lipolytica strains overexpressing DGA2 in multicopy. Appl Microbiol Biotechnol [Epub ahead of print].

Leplat, C., Nicaud, J.-M., Rossignol, T., (2015). High-throughput transformation method for Yarrowia lipolytica mutant library screening.FEMS Yeast Res [Epub ahead of print]

Sarilar V, Devillers H, Freel KC, Schacherer J & Neuveglise C (2015) Draft Genome Sequence of Lachancea lanzarotensis CBS 12615T, an Ascomycetous Yeast Isolated from Grapes. Genome Announc 3.

Sarilar V, Bleykasten-Grosshans C & Neuveglise C (2015) Evolutionary dynamics of hAT DNA transposon families in Saccharomycetaceae. Genome Biol Evol 7: 172-190.


Beopoulos A, Verbeke J, Bordes F, Guicherd M, Bressy M, Marty A & Nicaud JM (2014) Metabolic engineering for ricinoleic acid production in the oleaginous yeast Yarrowia lipolytica. Appl Microbiol Biotechnol 98: 251-262.

Dulermo R, Gamboa-Melendez H, Dulermo T, Thevenieau F & Nicaud JM (2014) The fatty acid transport protein Fat1p is involved in the export of fatty acids from lipid bodies in Yarrowia lipolytica. FEMS Yeast Res 14: 883-896.

Duquesne S, Bozonnet S, Bordes F, Dumon C, Nicaud JM & Marty A (2014) Construction of a highly active xylanase displaying oleaginous yeast: comparison of anchoring systems. PLoS One 9: e95128.

Freel KC, Sarilar V, Neuveglise C, Devillers H, Friedrich A & Schacherer J (2014) Genome Sequence of the Yeast Cyberlindnera fabianii (Hansenula fabianii). Genome Announc 2.

Groenewald M, Boekhout T, Neuveglise C, Gaillardin C, van Dijck PW & Wyss M (2014) Yarrowia lipolytica: safety assessment of an oleaginous yeast with a great industrial potential. Crit Rev Microbiol 40: 187-206.

Janbon, G., Ormerod, K.L., Paulet, D., Byrnes, E.J., 3rd, Yadav, V., Chatterjee, G., Mullapudi, N., Hon, C.C., Billmyre, R.B., Brunel, F., Bahn, Y.S., Chen, W., Chen, Y., Chow, E.W., Coppee, J.Y., Floyd-Averette, A., Gaillardin, C., Gerik, K.J., Goldberg, J., Gonzalez-Hilarion, S., Gujja, S., Hamlin, J.L., Hsueh, Y.P., Ianiri, G., Jones, S., Kodira, C.D., Kozubowski, L., Lam, W., Marra, M., Mesner, L.D., Mieczkowski, P.A., Moyrand, F., Nielsen, K., Proux, C., Rossignol, T., Schein, J.E., Sun, S., Wollschlaeger, C., Wood, I.A., Zeng, Q., Neuveglise, C., Newlon, C.S., Perfect, J.R., Lodge, J.K., Idnurm, A., Stajich, J.E., Kronstad, J.W., Sanyal, K., Heitman, J., Fraser, J.A., Cuomo, C.A., Dietrich, F.S., (2014). Analysis of the genome and transcriptome of Cryptococcus neoformans var. grubii reveals complex RNA expression and microevolution leading to virulence attenuation. PLoS Genet. 10, e1004261.

Kunze, G., Gaillardin, C., Czernicka, M., Durrens, P., Martin, T., Boer, E., Gabaldon, T., Cruz, J.A., Talla, E., Marck, C., Goffeau, A., Barbe, V., Baret, P., Baronian, K., Beier, S., Bleykasten, C., Bode, R., Casaregola, S., Despons, L., Fairhead, C., Giersberg, M., Gierski, P.P., Hahnel, U., Hartmann, A., Jankowska, D., Jubin, C., Jung, P., Lafontaine, I., Leh-Louis, V., Lemaire, M., Marcet-Houben, M., Mascher, M., Morel, G., Richard, G.F., Riechen, J., Sacerdot, C., Sarkar, A., Savel, G., Schacherer, J., Sherman, D.J., Stein, N., Straub, M.L., Thierry, A., Trautwein-Schult, A., Vacherie, B., Westhof, E., Worch, S., Dujon, B., Souciet, J.L., Wincker, P., Scholz, U., Neuveglise, C., (2014). The complete genome of Blastobotrys (Arxula) adeninivorans LS3 - a yeast of biotechnological interest. Biotechnol Biofuels. 7, 66.

Lazar Z, Dulermo T, Neuveglise C, Crutz-Le Coq AM & Nicaud JM (2014) Hexokinase-A limiting factor in lipid production from fructose in Yarrowia lipolytica. Metab Eng 26C: 89-99.

Maguire SL, Wang C, Holland LM, Brunel F, Neuveglise C, Nicaud JM, Zavrel M, White TC, Wolfe KH & Butler G (2014) Zinc finger transcription factors displaced SREBP proteins as the major Sterol regulators during Saccharomycotina evolution. PLoS Genet 10: e1004076.

Morin N, Calcas X, Devillers H, Durrens P, Sherman DJ, Nicaud JM & Neuveglise C (2014) Draft Genome Sequence of Rhodosporidium toruloides CECT1137, an Oleaginous Yeast of Biotechnological Interest. Genome Announc 2.

Morin, N., Crutz-Le Coq, A.-M., Rossignol, T., Nicaud, J.-M., (2014). Protocols for Monitoring Growth and Lipid Accumulation in Oleaginous Yeasts. In: T. J. McGenity (Ed.), Hydrocarbon and Lipid Microbiology Protocols, Humana Press, pp. 1-17.


Dulermo T, Treton B, Beopoulos A, Kabran Gnankon AP, Haddouche R & Nicaud JM (2013) Characterization of the two intracellular lipases of Y. lipolytica encoded by TGL3 and TGL4 genes: new insights into the role of intracellular lipases and lipid body organisation. Biochim Biophys Acta 1831: 1486-1495.

Gabaldon, T., Martin, T., Marcet-Houben, M., Durrens, P., Bolotin-Fukuhara, M., Lespinet, O., Arnaise, S., Boisnard, S., Aguileta, G., Atanasova, R., Bouchier, C., Couloux, A., Creno, S., Almeida Cruz, J., Devillers, H., Enache-Angoulvant, A., Guitard, J., Jaouen, L., Ma, L., Marck, C., Neuveglise, C., Pelletier, E., Pinard, A., Poulain, J., Recoquillay, J., Westhof, E., Wincker, P., Dujon, B., Hennequin, C., Fairhead, C., (2013). Comparative genomics of emerging pathogens in the Candida glabrata clade. BMC Genomics. 14, 623.

Galeote V, Bigey F, Devillers H, Neuveglise C & Dequin S (2013) Genome Sequence of the Food Spoilage Yeast Zygosaccharomyces bailii CLIB 213T. Genome Announc 1.

Groenewald, M., Boekhout, T., Neuveglise, C., Gaillardin, C., van Dijck, P. W. and Wyss, M. (2013). Yarrowia lipolytica: Safety assessment of an oleaginous yeast with a great industrial potential. Crit Rev Microbiol. 

Kominek J, Marszalek J, Neuveglise C, Craig EA & Williams BL (2013) The complex evolutionary dynamics of Hsp70s: a genomic and functional perspective. Genome Biol Evol 5: 2460-2477.

Lazar Z, Rossignol T, Verbeke J, Crutz-Le Coq AM, Nicaud JM & Robak M (2013) Optimized invertase expression and secretion cassette for improving Yarrowia lipolytica growth on sucrose for industrial applications. J Ind Microbiol Biotechnol 40: 1273-1283.

Michely, S., Gaillardin, C., Nicaud, J. M. and Neuveglise, C. (2013). Comparative physiology of oleaginous species from the yarrowia clade. PLoS One 8, e63356

Verbeke, J., Beopoulos, A. and Nicaud, J. M. (2013). Efficient homologous recombination with short length flanking fragments in Ku70 deficient Yarrowia lipolytica strains. Biotechnol Lett 35, 571-6.

Papanikolaou S, Beopoulos A, Koletti A, Thevenieau F, Koutinas AA, Nicaud JM & Aggelis G (2013) Importance of the methyl-citrate cycle on glycerol metabolism in the yeast Yarrowia lipolytica. J Biotechnol 168: 303-314.


Theerachat, M., Emond, S., Cambon, E., Bordes, F., Marty, A., Nicaud, J. M., Chulalaksananukul, W., Guieysse, D., Remaud-Simeon, M. and Morel, S. (2012). Engineering and production of laccase from Trametes versicolor in the yeast Yarrowia lipolytica.  and Kallel, H. (2012). Production and characterization of human granulocyte-macrophage colony-stimulating factor (hGM-CSF) expressed in the oleaginous yeast Yarrowia lipolytica. Appl Microbiol Biotechnol 96, 89-101

Loira, N., Dulermo, T., Nicaud, J. M. and Sherman, D. J. (2012). A genome-scale metabolic model of the lipid-accumulating yeast Yarrowia lipolytica. BMC Syst Biol 6, 35. 

Nicaud, J. M. (2012). Yarrowia lipolytica. Yeast 29, 409-18.

 Ogrydziak, D. M. and Nicaud, J. M. (2012). Characterization of Yarrowia lipolytica XPR2 multi-copy strains over-producing alkaline extracellular protease - a system for rapidly increasing secretory pathway cargo loads. FEMS Yeast Res 12, 938-48.

 (2012). Identification and characterization of DGA2, an acyltransferase of the DGAT1 acyl-CoA:diacylglycerol acyltransferase family in the oleaginous yeast Yarrowia lipolytica. New insights into the storage lipid metabolism of oleaginous yeasts. Appl Microbiol Biotechnol 93, 1523-37. 

Duquesne, S., Bordes, F., Fudalej, F., Nicaud, J. M. and Marty, A. (2012). The Yeast Yarrowia lipolytica as a Generic Tool for Molecular Evolution of Enzymes. Methods Mol Biol 861, 301-12.

Gaillardin, C., Neuveglise, C., Kerscher, S. and Nicaud, J. M. (2012). Mitochondrial genomes of yeasts of the Yarrowia clade. FEMS Yeast Res 12, 317-31.

Louis, V. L., Despons, L., Friedrich, A., Martin, T., Durrens, P., Casaregola, S., Neuveglise, C., Fairhead, C., Marck, C., Cruz, J. A., Straub, M. L., Kugler, V., Sacerdot, C., Uzunov, Z., Thierry, A., Weiss, S., Bleykasten, C., De Montigny, J., Jacques, N., Jung, P., Lemaire, M., Mallet, S., Morel, G., Richard, G. F., Sarkar, A., Savel, G., Schacherer, J., Seret, M. L., Talla, E., Samson, G., Jubin, C., Poulain, J., Vacherie, B., Barbe, V., Pelletier, E., Sherman, D. J., Westhof, E., Weissenbach, J., Baret, P. V., Wincker, P., Gaillardin, C., Dujon, B. and Souciet, J. L. (2012). Pichia sorbitophila, an Interspecies Yeast Hybrid, Reveals Early Steps of Genome Resolution After Polyploidization. G3 (Bethesda) 2, 299-311. 

Kabran, P., Rossignol, T., Gaillardin, C., Nicaud, J. M. and Neuveglise, C. (2012). Alternative Splicing Regulates Targeting of Malate Dehydrogenase in Yarrowia lipolytica. DNA Res 19, 231-44. 


Amselem, J., Cuomo, C. A., van Kan, J. A., Viaud, M., Benito, E. P., Couloux, A., Coutinho, P. M., de Vries, R. P., Dyer, P. S., Fillinger, S., Fournier, E., Gout, L., Hahn, M., Kohn, L., Lapalu, N., Plummer, K. M., Pradier, J. M., Quevillon, E., Sharon, A., Simon, A., ten Have, A., Tudzynski, B., Tudzynski, P., Wincker, P., Andrew, M., Anthouard, V., Beever, R. E., Beffa, R., Benoit, I., Bouzid, O., Brault, B., Chen, Z., Choquer, M., Collemare, J., Cotton, P., Danchin, E. G., Da Silva, C., Gautier, A., Giraud, C., Giraud, T., Gonzalez, C., Grossetete, S., Guldener, U., Henrissat, B., Howlett, B. J., Kodira, C., Kretschmer, M., Lappartient, A., Leroch, M., Levis, C., Mauceli, E., Neuveglise, C., Oeser, B., Pearson, M., Poulain, J., Poussereau, N., Quesneville, H., Rascle, C., Schumacher, J., Segurens, B., Sexton, A., Silva, E., Sirven, C., Soanes, D. M., Talbot, N. J., Templeton, M., Yandava, C., Yarden, O., Zeng, Q., Rollins, J. A., Lebrun, M. H. and Dickman, M. (2011). Genomic analysis of the necrotrophic fungal pathogens Sclerotinia sclerotiorum and Botrytis cinerea. PLoS Genet 7, e1002230.

 (2011). Involvement of the G3P shuttle and beta-oxidation pathway in the control of TAG synthesis and lipid accumulation in Yarrowia lipolytica. Metab Eng 13, 482-91. 

Fickers, P., Marty, A. and Nicaud, J. M. (2011). The lipases from Yarrowia lipolytica: genetics, production, regulation, biochemical characterization and biotechnological applications. Biotechnol Adv 29, 632-44. 

Gasmi, N., Ayed, A., Ammar, B. B., Zrigui, R., Nicaud, J. M. and Kallel, H. (2011). Development of a cultivation process for the enhancement of human interferon alpha 2b production in the oleaginous yeast, Yarrowia lipolytica. Microb Cell Fact 10, 90. 

Gasmi, N., Ayed, A., Nicaud, J. M. and Kallel, H. (2011). Design of an efficient medium for heterologous protein production in Yarrowia lipolytica: case of human interferon alpha 2b. Microb Cell Fact 10, 38. 

Gasmi, N., Fudalej, F., Kallel, H. and Nicaud, J. M. (2011). A molecular approach to optimize hIFN alpha2b expression and secretion in Yarrowia lipolytica. Appl Microbiol Biotechnol 89, 109-19.  

Haddouche, R., Poirier, Y., Delessert, S., Sabirova, J., Pagot, Y., Neuveglise, C. and Nicaud, J. M. (2011). Engineering polyhydroxyalkanoate content and monomer composition in the oleaginous yeast Yarrowia lipolytica by modifying the ss-oxidation multifunctional protein. Appl Microbiol Biotechnol 91, 1327-40.

 Morin, N., Cescut, J., Beopoulos, A., Lelandais, G., Le Berre, V., Uribelarrea, J. L., Molina-Jouve, C. and Nicaud, J. M. (2011). Transcriptomic analyses during the transition from biomass production to lipid accumulation in the oleaginous yeast Yarrowia lipolytica. PLoS One 6, e27966.

Neuveglise, C., Marck, C. and Gaillardin, C. (2011). The intronome of budding yeasts. CR Biol 334, 662-70.

Nguyen, H. V., Legras, J. L., Neuveglise, C. and Gaillardin, C. (2011). Deciphering the hybridisation history leading to the Lager lineage based on the mosaic genomes of Saccharomyces bayanus strains NBRC1948 and CBS380. PLoS One 6, e25821.

Sabirova, J. S., Becker, A., Lunsdorf, H., Nicaud, J. M., Timmis, K. N. and Golyshin, P. N. (2011). Transcriptional profiling of the marine oil-degrading bacterium Alcanivorax borkumensis during growth on n-alkanes. FEMS Microbiol Lett 319, 160-8.

Sabirova, J. S., Haddouche, R., Van Bogaert, I. N., Mulaa, F., Verstraete, W., Timmis, K. N., Schmidt-Dannert, C., Nicaud, J. M. and Soetaert, W. (2011). The 'LipoYeasts' project: using the oleaginous yeast Yarrowia lipolytica in combination with specific bacterial genes for the bioconversion of lipids, fats and oils into high-value products. Microb Biotechnol 4, 47-54.



Chuang, L. T., Chen, D. C., Nicaud, J. M., Madzak, C., Chen, Y. H. and Huang, Y. S. (2010). Co-expression of heterologous desaturase genes in Yarrowia lipolytica. N Biotechnol 27, 277-82.

Desfougeres, T., Haddouche, R., Fudalej, F., Neuveglise, C. and Nicaud, J. M. (2010). SOA genes encode proteins controlling lipase expression in response to triacylglycerol utilization in the yeast Yarrowia lipolytica. FEMS Yeast Res 10, 93-103.

 Emond, S., Montanier, C., Nicaud, J. M., Marty, A., Monsan, P., Andre, I. and Remaud-Simeon, M. (2010). New efficient recombinant expression system to engineer Candida antarctica lipase B. Appl Environ Microbiol 76, 2684-7.

 Haddouche, R., Delessert, S., Sabirova, J., Neuveglise, C., Poirier, Y. and Nicaud, J. M. (2010). Roles of multiple acyl-CoA oxidases in the routing of carbon flow towards beta-oxidation and polyhydroxyalkanoate biosynthesis in Yarrowia lipolytica. FEMS Yeast Res 10, 917-27.

 Lasserre, J. P., Nicaud, J. M., Pagot, Y., Joubert-Caron, R., Caron, M. and Hardouin, J. (2010). First complexomic study of alkane-binding protein complexes in the yeast Yarrowia lipolytica. Talanta 80, 1576-85.

 Mekouar, M., Blanc-Lenfle, I., Ozanne, C., Da Silva, C., Cruaud, C., Wincker, P., Gaillardin, C. and Neuveglise, C. (2010). Detection and analysis of alternative splicing in Yarrowia lipolytica reveal structural constraints facilitating nonsense-mediated decay of intron-retaining transcripts. Genome Biol 11, R65.