Synthetic biology tools for mammalian cell engineering
Our lab at Imperial College is focused on the engineering of bacteria, mammalian and synthetic cells to advance the applications of synthetic biology. Resource competition between host cells and genetic constructs is one of our main research themes, for its impact on our ability to reliably engineer cellular hosts. In order to tackle resource competition and the cellular burden derived from it, we are currently developing novel tools to address measure and characterise competition in mammalian cells, building on our previous work in bacteria, but also exploring the design of novel gene expression control platforms for low-footprint genetic engineering.
Short bio
Francesca is Senior Lecturer (Associate Professor) at Imperial College London. She has track record in host-aware gene construct design for synthetic biology. Her group currently focuses on developing novel strategies for improved gene expression control in bacteria, mammalian and synthetic cells.
Laboratory of the speaker
Imperial College London
Invited by
Manish KUSHWAHA & Olivier BORKOWSKI