Alba DE SAN EUSTAQUIO CAMPILLO

Alba DE SAN EUSTAQUIO CAMPILLO

PhD Student (supervisor : A. Chastanet)

  • Alba DE SAN EUSTAQUIO CAMPILLO
  • Position held in the Lab : PhD student
  • In the Lab: from 01/09/2013 since 31/03/2017

Project Description:

Project title : Control of bacterial cell wall biosynthesis in Bacillus subtilis.
Co-supervision by Rut Carballido-Lopez (Micalis) and Vincent Fromion (MIG)
Although the chemical composition of the bacterial cell wall (CW) is well known, the factors controlling CW synthesis and structure remain largely unknown. The first step of my project is to reveal meaningful sets of gene modules involved in the control of CW biogenesis in Bacillus subtilis. Then, analysis of the activity patterns of the different pathways will pinpoint mechanistic details involved in the synthesis and maturation of the individual CW polymers and of both the sidewall (elongation) and the crosswall (septation). The biological significance of the models will be validated and refined by experimental approaches.

Publications:

Goosens VJ, De-San-Eustaquio-Campillo A, Carballido-López R, van Dijl JM. A Tat ménage à trois - The role of Bacillus subtilis TatAc in twin-arginine protein translocation. Biochim Biophys Acta. 2015 Aug 1.

Modification date : 14 September 2023 | Publication date : 29 April 2015 | Redactor : Cyrille Billaudeau