AMIPEM
Food, Gut microbiota, Brain and Metabolic Diseases The importance of the intestinal microbiota for the physiology of the host and its involvement in the development of physio-pathological phenomena are increasingly recognised. In this context, our research focuses on the study of the gut microbiota-food interaction as a factor of vulnerability to the development of human […]
ChemSyBio
Biochemistry and Synthetic Biology The human microbiome plays a central role in human physiology. This complex ecosystem is composed of thousands of bacterial species and has a remarkable biosynthetic potential. However, we still have a limited knowledge of its biosynthetic potential and the enzymes that support its functions. In the ChemSyBio team, we have shown […]
FInE
Functionality of the Intestinal Ecosystem The human intestinal microbiota, as we know it today, appears to be very complex. In order to move towards a holistic understanding of the gut microbiota, including its non-cultivable component, which is still in the majority to date, we have contributed to the development of a new and powerful approach, […]
FME
Food Microbial Ecology Understanding the microbial ecology of the food chain: towards more sustainable and healthy food. The FME lab focuses its research on understanding the mechanisms by which bacteria and fungi interact with food products during spoilage and fermentation. In particular, our team is trying to understand how food microbial diversity may be leveraged […]
MIHA
Microbiota Interactions with Human and Animal The Microbiota Interactions with Human and Animal (MIHA) team at INRAE is interested in studying the interactions between the intestinal microbiota and its host and their role in digestive inflammation. More specifically, we are focusing on analyzing the functions of the microbiome that are modulated in inflammatory conditions. In […]
NutriPhage
Diet-driven dynamics of the gut virome In our team, we study human gut viruses, with a particular focus on those infecting bacteria (phages). A substantial majority of gut bacteria harbor phages in their genomes (prophages). These phages can be activated (induced), through mechanisms not yet fully understood, and have the strong potential to shape the […]
PhylHom
Phylogeny and Physiology of the Human Microbiome The PhylHom team focuses on the human microbiome and the impact of xenobiotics (dietary and environmental exposures, drugs, etc) on these complex ecosystems, combining skills in microbial ecology, anaerobic microbiology, and meta-omics. The impact of exposures on the microbiome is determined in a range of health-associated and pathological […]
ProbiHôte
Commensal and Probiotic Microorganisms-Host Interactions Our four major objectives are: To study intestinal and pulmonary microbial ecosystems in order to identify potential beneficial effects on the host as well as their mechanisms of action To explore the immune and physiological responses of the host to bacteria and fungi, commensal and probiotic bacteria in different […]