CellComp
Cellular Computing The Cellular Computing team aims to engineer synthetic genetic circuits with increasing levels of complexity: going from the molecular-level in cell-free systems to the multicellular level in co-cultures, with intercellular exchange. By integrating experimental data with mathematical modelling, we strive to understand and predict the behaviour of these circuits, facilitating optimisation and scaling […]
SyBER
Systems Biology for bacterial Engineering and Redesign Synthetic Biology aims to engineer biological systems for applications in health, biomanufacturing, and the environment. However, challenges persist due to limited well-characterized genetic elements, undesired interactions, and the necessity to explore novel biological functions. To tackle these challenges, the SyBER team employs multidisciplinary approaches, including cutting-edge genome engineering […]
Bio-RetroSynth
Retro Synthetic Biology The BRS team specializes in synthetic biology. Within this field, the team is designing and engineering metabolic pathways and genetic circuits for bioproduction, biosensing and biocomputation in whole-cell (E. coli) and cell-free systems. The team is organized in a dry lab composed of data scientists and computational biologists, and a wet lab […]
COSYNUS
Synthetic communities and microbial cell factories Cosynus is dedicated to creating innovative strategies for bioproduction from microbial cell factories by utilizing renewable carbon sources as a sustainable alternative to petrochemical sources. We are actively working on implementing synthetic biology tools and strategies to transform our chassis strain, the yeast Yarrowia lipolytica, into an industrial cell […]
MuSE
Mutagenesis in Single-Cells and Evolution Mutations, i.e. changes in the genetic sequence of organisms, are the driving force of evolution. They also have important consequences for human health. Our fight against infectious diseases is underpinned by an evolutionary arms race with pathogens, in which mutations fuel the evolution of virulence, antibiotic resistance and bacteriophage escape. […]
ProCeD
Prokaryotic Cell Development We are interested in understanding how dynamic molecular interactions are regulated in time and in space to form functional machineries that establish long-range orders and cellular functions in bacteria, with a particular focus on the bacterial cytoskeleton and on the cell envelope, at the frontline of environmental and host-pathogen interactions. To this […]