Understanding the intracellular dormancy of Listeria monocytogenes
Listeria monocytogenes (Lm) is a widespread pathogenic bacterium that causes listeriosis, a rare foodborne disease with one of the highest mortality rates among foodborne infections. Lm was long thought to live only in the cytosol of infected cells, but it is now known that it can also persist inside vacuolar compartments called LisCVs (Listeria-containing vacuoles). […]
Lydia Palaiodimou – 17/12/2024
Molecular Insights into L. monocytogenes Persistence via Label-Free Quantitative Proteomics
Aquatic environment drives the emergence of cell wall-deficient dormant forms in Listeria
Bacteria can respond to environmental stresses by entering a dormant state called viable but non-culturable (VBNC) state. VBNC bacteria lose the ability to grow in routine culture media. Pathogens entering a VBNC state pose a significantly risk for human and animal health, as they are not detected by standard growth-based techniques, and can “wake up” […]