Vinciane is a senior researcher in the team “Interactions of commensal and probiotic microorganisms with the host”, co-heading the group “Microbiota-Digestive and Respiratory Health” since 2023. After completing her PhD (2009) on the modulation of inflammation in the airway epithelium in Cystic Fibrosis (CF), she studied the impact of hormones on ion and fluid transport in the CF airways in Prof. Brian Harvey’s lab in Dublin. She came back to France in 2013 where she joined a team in Pasteur Institute (D2i, Prof. Jean-Michel Sallenave’s group), to investigate, in vitro and in vivo, the role of a bacterial elastase on the airway homeostasis, particularly, the epithelial repair process, ion transport and inflammatory response. She then moved to Dr Mike Gray’s lab in Newcastle-upon-Tyne in 2015 to explore alternative approaches to activate chloride and bicarbonate secretion in the CF airways. Particularly, she developed an in vitro method to study the airway luminal pH and investigated the role of multiple ion channels and transporters in airway pH homeostasis. Since she was recruited at INRA in 2019, she focuses her research on the pulmonary microbiota and the gut-lung axis and has established in vitro models of fully differenciated primary human nasal and bronchial epithelial cells to explore the interactions between the microbiota and the host’s lungs.
ORCID: 0000-0003-0042-3735
Google Scholar: https://scholar.google.co.uk/citations?user=P9daAckAAAAJ&hl=en
