By combining 3D imaging and artificial intelligence, two recent scientific publications have opened a new path to design protective biofilms.
Gut microbiota regulation of enteroendocrine cells along the gut: towards a role for cell metabolism.
Peer Community In and Peer Community Journal: from preprint recommendation to diamond open access publication
A Self Driving Lab for Accelerating the Engineering of Biological Systems for Sustainable Production
Biological sex and microbiota drive DNA methylation patterns in the mouse liver
Development of cell-free systems to refine our understanding of bacterial physiology
Origins and Rate of Spontaneous Mutations in the Bacteriophage Lambda
Phage–bacteria interactions shaping the ecology of plant diseases
Natural genetic transformation is integrated into the cell cycle of pneumococcus. The pathogenic bacterium S. pneumoniae, commonly known as pneumococcus,
Clostridioides difficile is a Gram-positive, strictly anaerobic, spore-forming bacterium responsible for nosocomial and community-acquired intestinal infections. One of the major
Multiscale fluorescence imaging of Pseudomonas aeruginosa: from cell morphogenesis to antibiotic resensitization
The gastrointestinal tract is a reservoir of opportunistic pathogens, where pathobionts take advantage of dysbiosis to proliferate in immunocompromised patients.
Project Background Bioengineering of genetic and metabolic circuits has a wide range of applications. However, most efforts in circuit design
A new strategy to combat antibiotic resistance A consortium of researchers with multidisciplinary skills, coordinated by INRAE and including the
The growth-laws cookbook: Ingredients and recipes for mechanistic models of ribosome allocation in bacteria and beyond
The corrinoid model illuminates microbial community interactions across scales
The annual meeting of Alibiote, one of our transversal research axis, took place on Tuesday, March 18. It was an
Distributed Biological Circuits in Synthetic Phage-Bacterial Systems
Adaptation of Staphylococcus aureus to Natural Environments and Aptamer-Based Sensing
Exploring natural products diversity and complexity
Analysis of microbial function creating novel biotechnology tools for food, medical, and chemical industries
Inès Doublier was selected, along with 13 other candidates, to take part in the local grand final 2025 of “Three
Antibiotic-induced morphological changes boost viral predation on bacterial hosts
Human Microbiome: From Models and Mechanism to Medicine
High-Throughput Exploration of Sequence Space at Gene and Genome Scales
Discovery of Mushuviridae phages that interact with human health-related gut bacteria
Integrating Multi-Omics to Address Unanswered Questions in Women’s Health: Insights into Endometriosis, Adenomyosis, and Beyond
Study of Enterococcus faecalis intracellular multiplication in hepatocytes
Des microbiotes de l’environnement au microbiote intestinal
Human Microbiome: From Models and Mechanism to Medicine
Anais Lemoine, a paediatrician at APHP’s Trousseau hospital, did her PhD at Micalis, in the Probihôte team. This study is
New insights on the biogenesis of Coxiella replicative niches revealed by lipid profilig
Unraveling the Communication Systems of Gram-Positive Bacteria and Their Mobile Genetic Elements
Epitranscriptomic response to antibiotics in Vibrio cholerae
In the field of Synthetic Biology, biological systems are engineered to sense inputs and respond in a programmed manner, a
Our annual symposium took place on Friday, December 6, 2024. It was a great success! Philippe Langella, INRAE laureate,
The project will be carried out in the research team “Cosynus” led by Tristan Rossignol and Young-Kyoung Park in Micalis
Molecular Insights into L. monocytogenes Persistence via Label-Free Quantitative Proteomics
Mechanisms of microbiome adaptation to chronic exposure to xenobiotics and its impact on secondary treatment responses
Construction and directed evolution of mutualistic synthetic consortia of Bacillus subtilis
The effect of membrane fluidity on cell wall shape and elongation in Bacillus subtilis
Caractérisation des biofilms in vitro et évaluation de la diversité génomique et de la transmission de Clostridioides difficile
Impact of bacterial biofilm adaptation to biocides on antibiotic resistance
The pathogen Streptococcus pyogenes (Group A Streptococcus; GAS) causes severe infections with long-term sequellae. GAS infections account for 517,000 deaths
Bacteria can respond to environmental stresses by entering a dormant state called viable but non-culturable (VBNC) state. VBNC bacteria lose
Engineering prokaryotic translation regulation with eukaryotic RNA-binding proteins
Elucidation and application of the bacterial inositol metabolic system
From livestock buildings to the International Space Station, and even in our toothbrushes, biofilms, composed of three-dimensional microbial communities, have
The B3D team is thrilled to participate in a new COST Action, officially launched in Brussels on September 26th. This
Long-term alteration of host-microbiota intestinal symbiosis by dietary modulation in a murine model
Deciphering the mechanisms of cold adaptation when Listeria monocytogenes uses food unsaturated lipid
Membrane fluidity is a critical element in bacterial phenotype: it is the parameter that governs the rate of diffusion of
First observation by electron microscopy of pairs of organised protofilaments and first three-dimensional structure of the bacterial homologue of MreB
Comprehensive study of the microbiome of fermented vegetables using integrative approaches
Innovative approaches to food preservation and safety: development of active packaging and advanced microbiological screening
From livestock buildings to the International Space Station, and even in our toothbrushes, biofilms, composed of three-dimensional microbial communities, have
From eukaryotic to bacterial cells, cytoskeletal proteins play critical roles in various aspect of cell physiology, including cell shape and
The Phenomenon of Cellular Senescence in CancerIsaias Balderas Renteria
On-chip large-scale-integration of genetically programmed artificial cells
Non-conventional substrates, yeasts, and strategies for biomanufacturing
